Japanʼs history for combatting
infectious diseases

In 1930s and 1940s Japan, malaria, TB, schistosomiasis, and
soil-transmitted helminths were endemic.

In order to address these issues, community-based public health programs organized by government leaders,
healthcare professionals, researchers, and individual citizens resulted in the effective elimination
and subsequent eradication of these diseases in Japan in the 1960s and 1970s.

The world recognized Japanʼs recovery and rapid economic growth during the decade following World War II
as nothing short of miraculous.
The countryʼs game-changing post-war public health programs now
form the basis of many WHO disease elimination strategies.

After several decades of increasing scientific and public health successes domestically,
as well as overseas development aid globally, in the 1990s Japan also catalyzed numerous
major global health initiatives, such as the Hashimoto Initiative
to support international parasite control.

Japan also played a major role in creating the Global Fund to Fight AIDS, Tuberculosis, and Malaria.

In 2013, GHIT Fund, the world's first public-private global health R&D fund was established.

Today, in tireless continuation of its quest to eliminate infectious diseases,
the GHIT Fund serves as a catalyst to the development of new
and much needed pharmaceuticals

for global health by leveraging Japanʼs
technology and innovation.

1930

1930
Tuberculosis: The #1 killer Tuberculosis: Over 250,000 die annually, over 1.5 million infected

1945

1945
Over 70% of Japan's population, infected with Soil Transmitted Helminths Over 400,000 soldiers return, infected with Malaria

1948

1948
Self-sufficient in penicillin production Fewer deaths by infectious disease

1949

1949
‘No Flies, No Mosquitoes’ campaign of DDT spraying starts Streptomycin introduced clinically in Japan Drastic reduction of deaths by Tuberculosis

1950

1950
Japan synthesizes Supatonin [Diethylcarbamazine (DEC) citrate] for ascariasis and lymphatic filariasis

1951

1951
Japan Antituberculosis Association formed, Tuberculosis Prevention Act enacted

1955

1955
Founding of Japan Association of Parasite Control (JAPC)
1955
Water Supply Law enacted

1958

1958
Universal Healthcare insurance achieved
1958
School Health Law enacted

1961

1961
Japan eradicates Malaria

1965

1965
Start of ‘Zero parasite’ campaign in Okinawa

1973

1973
Professor Omura of Kitasato University discovers Streptomyces avermectinius, the active ingredient of avermectin

1974

1974
Asian Parasitology Control Organization (APCO) launched

1977

1977
Japan eradicates Schistosomiasis

1978

1978
Japan eradicates Lymphatic Filariasis

1980

1980
Global elimination of smallpox

1989

1989
To eradicate Guinea worm in West Adrica, Japan committed 100 million Yen/ 8 years for grant aid

1996

1996
Prevalence of soil-transmitted helminth decreased by 0.01% in Japan

2000

2000
Okinawa Infectious Diseases Initiative
2000
Asian Centre of International Parasite Control established in Thailand

2001

2001
Eastern and Southern Africa Centre of International Parasite Control (ESACIPAC) established at the Kenya Medical Research Institute (KEMRI), Nairobi

2004

2004
West African Centre for International Parasite Control (WACIPAC) established at the Noguchi Memorial Institute for Medical Research, Accra, Ghana

2012

2012.7

July, 2012
GHIT Fund Launch Committee established

2013

2013.2

February, 2013
Middle East Respiratory Syndrome (MERS) reported throughout Saudi Arabia

2013.5

May, 2013
GHIT launch event at the World Health Assembly in Geneva
May, 2013
Financial Times
Japan in pioneering partnerships to fund global health research
May, 2013
Japan developed the Strategy for Global Health Diplomacy

2013.6

June, 2013
Japan developed the Revitalization Strategy
June, 2013
GHIT press conference at TICAD V in Yokohama

2014

2014.3

March, 2014
Cumulative Investment USD 19.1 Million
March, 2014
Cumulative Number of Invested Partnerships
March, 2014
Hit-to-Lead Platform Launches

2014.7

July, 2014
Nature
Global Health R&D Showcase
July, 2014
Japan developed the Healthcare and Medical Strategy

2014.8

August, 2014
GHIT convenes 1st proposal writing seminar at the University of Tokyo
August, 2014
Dengue fever reported in Japan for the first time in 70 years

2014.11

November, 2014
GHIT facilitates discussion on academia's role in global health R&D at “Global Health Innovation Through Partnership" symposium
November, 2014
GHIT convenes 2nd proposal writing seminar at the Joint conference of the 55th Annual Meeting of Japanese Society of Tropical Medicine and the 29th Annual Meeting of the Japan Association for International Health
November, 2014
GHIT and prodiuct development partners discuss "Partnership-Driven Innovation" with product development partners at Embassy of Japan in the UK

2015

2015.2

February, 2015
Target Research Platform Launches

2015.3

March, 2015
Cumulative Investment USD 46.1 Million
March, 2015
Cumulative Number of Invested Partnerships

2015.4

April, 2015
GHIT convenes 3rd proposal writing seminar in Osaka
April, 2015
GHIT leaders discuss Japan's private sector's contribution to global health R&D at World Health Summit Regional Meeting in Kyoto
April, 2015
Forbes
Investing In Drugs That Won't Make Money

2015.9

September, 2015
United Nations General Assembly adopts Sustainable Development Goals

2017

2017.2

February, 2017
GHIT convenes 6th proposal writing seminar at Osaka University

2017.3

March, 2017
Cumulative Investment USD 98.6 Million
March, 2017
Cumulative Number of Invested Partnerships